UMH - GENETIC ENGINEERING

GENETIC ENGINEERING

Course

Code: 1401

Degree: Bachelor's in Biotechnology

Faculty of Experimental Sciences

Year: Year 2 of Bachelor's in Biotechnology

Semester: Fall

Type: Required

Language: Spanish

ECTS credits: 6

Lecture: 3

Laboratory: 3

Hours: 150

Directed: 60

Shared: 30

Autonomous: 60

Subject matter: Molecular Bioengineering

Module: Bioengineering

Department: Applied Biology

Area: GENETICS

Course instructors are responsible for the course content descriptions in English.

Description

Methods of studying gene structure and function. Gene manipulation and transfer methods.

Faculty

Name	Coordinator	Lecture	Laboratory
MICOL MOLINA, JOSÉ LUIS	■	■	■
JOVER GIL, SARA			■

Professional interest

La Ingeniería Genética ha supuesto la mayor revolución metodológica que ha experimentado la Genética. Bajo las denominaciones de Ingeniería Genética y Biología Molecular trabaja en nuestros días un gran número de investigadores, que han desarrollado un amplísimo inventario de herramientas para el análisis y la manipulación de los genes. La Biotecnología Molecular ha nacido gracias al desarrollo de la Ingeniería Genética, lo que la convierte en una materia indispensable para cualquier estudiante del Grado en Biotecnología.

Competencies and learning outcomes

General competencies

Acquisition of basic scientific knowledge.
Capacity to identify, formulate, and resolve basic problems.
Ability to use the tools and instruments necessary for designing experiments and understanding the limits of the experimental approach.
Capacity to apply analytical and numerical methods for the analysis of problems.
Ability to implement efficient tools for troubleshooting within the field of knowledge.
Capacity for continuous improvement, experimentation, and innovation.
Critical and analytical skills in the field of the sciences.
Creative capacity within the field of the branch of knowledge.
Capacity to evaluate, optimize, and compare criteria in decision making.
Capacity to draft, represent, analyze, and interpret scientific documentation and relevant data within the branch of science.
Ability to transmit knowledge acquired in expert and non-expert environments.
Ability to work with multidisciplinary and multicultural teams.
Ability to update knowledge within the branch of sciences.
Social, ethical, and environmental commitment for the development of scientific solutions that are compatible and sustainable with the realities of human and natural environments.
Ability to adapt to and update new knowledge and scientific advances, adopting an ethical, innovative, and creative attitude in the practice of the profession.
Work properly in a biological laboratory with biological material, including the safe handling and elimination of biological and chemical residues while keeping an annotated record of activities.

Specific competencies

Ability to recognize and understand the molecular bases of biotechnological processes.
Acquire skills in instrumental and computation techniques used in biotechnology and know how to choose those most suitable for a specific biotechnological process.
Capacity to understand the importance of viruses in terms of their relevance as models for replication and gene expression, as well as tools in molecular biology.
Capacity to analyze the structure, variation, expression mechanisms in genes, and the methods for their study and handling.
Apply biological databases and the programs that allow organizing and analyzing them.
Ability to apply molecular procedures to increase the biotechnological potential in plants.

Objectives (Learning outcomes)

01Become familiar with techniques for the characterization and manipulation of nucleic acids
02Ability to understand and judge recent advances in Genetic Engineering
03Ability to interpret the experiments of Molecular Genetics and Genetic Engineering presented a selection of articles in scientific
04Ability to design simple experiments of Molecular Genetics and Genetic Engineering, using a scientifically minded
05An understanding of the usefulness of the most important enzymes for genetic engineering techniques, particularly polymerases, ligases and restrictases
06Learning strategies for nucleic acid cloning, caracterization and manipulation
07Aprenentatge de las tècnicas de amplificació, seqüenciació i modificació dels àcids nucleics, les seves aplicacions i la seva transcendència en molts camps de la Biologia
08Understanding techniques to the structural and functional characterization of genes, as well as enabling their controlled disturbance

Teaching units

Association between objectives and units

Objective/Unit	U1	U2	U3
01
02
03
04
05
06
07
08

Schedule

Week	Directed hours	Shared hours	Autonomous hours	Total hours
1	5	1	5	11
2	4	1	4	9
3	4	2.5	4	10.5
4	4.5	1	3	8.5
5	4.5	1	3	8.5
6	3	2.5	3	8.5
7	4.5	1	3	8.5
8	5	2.5	5	12.5
9	4.5	1	3	8.5
10	1	1	2	4
11	3	2.5	4	9.5
12	2	1	3	6
13	2	1	3	6
14	12	2.5	7	21.5
15	1	8.5	8	17.5

Basic bibliography

Complementary bibliography

Pierce, Benjamin A. Fernández Castelo, Silvia trad. "Genética un enfoque conceptual". Madrid Panamericana cop. 2006.

Methodology and grading

Methodology

Case studies: Learning through the analysis of actual or simulated cases in order to interpret and resolve them by employing various alternative solution procedures.
Lecture: Pass on knowledge and activate cognitive processes in students, encouraging their participation.
Problem-based learning: Develop active learning strategies through problem solving that promote thinking, experimentation, and decision making in the student.
Solving exercises and problems: Exercise, test, and apply previous knowledge through routine repetition.

Grading

Evaluation Method
The subject can be overcome by continuous assessment, racking up 100 points along the course by scoring activities (minimum score to pass the course: 50 points). Alternatively, take into account only the final exam score (50 points, minimum score to pass the course: 25 points). The final grade for the course will be the most favorable to the student of the two mentioned.
Students suspended or not retained for subsequent calls presented the cumulative score through continuous assessment, unless waived voluntarily wish, must tell the decision to begin the course professor.

Evaluation of theory
There will be a test that will be graded from 0 to 50 points. Included 35 questions, each with four alternative answers. Is awarded one point for each question answered correctly. 0.33 points will be deducted for each wrong answer. The unanswered questions are not scored negatively.
The review will also include two problems, each of which will be credited with up to 7.5 points. Mistakes made in the resolution of these problems will not be penalized. Although the student paper will be provided to facilitate the development of solutions to problems, scored only issued final answers in each section of the answer sheet.

Evaluation of classroom practices (problems)
1.5 points will be awarded for every problem solved well, up to a maximum of 30. The teacher give each section a score problem was 0, 0.5 or 1. For the overall score problem plus any partial and divided the result by the number of sections, applying rounding up the second decimal place, except when it is zero.
Those students whose answer sheets are selected by the teacher to his defense in public and are not present in the classroom will lose 30 points from your overall rating of the course. Also lost 30 points according to the teacher who is unable to defend minimally express the proposals in their answer sheets.

Evaluation of laboratory practice
Be awarded up to 10 points for attending practical classes (0.5 point per hour of class). There will be a practice exam, while the theory, which will consist of 10 questions with answers and alternatives will be credited with up to 10 points. 0.33 points will be deducted for each wrong answer. The unanswered questions are not scored negatively.

Advertising scoring assessment activities
Grades earned by solving problems will be published one day after the discussion of each series. The attendance for labs will be posted immediately after the last group of teaching practices. The part of the alternative answers questions of theory and practical exams will be posted on the day of the conclusion of the examination, and the share of problems, two days later.

Review of Grades
The review of the ratings of the series of problems according to the schedule will be published to this effect. The tests of theory and practice will be held at a date to be announced well in advance, in the Meeting Room of the Department of Applied Biology (Vinalopó building). Not be accepted at any time questions about how an activity was evaluated scoring.

Absences
Those missing the exam, whatever the cause, will be considered not shown for all purposes. Those who miss a session of the labs is suffering from a disease or been summoned to an examination of another subject's Degree in Biotechnology not lose the corresponding score. This exemption shall be granted only once per student and after emailing a medical certificate or document evidencing the holding of the examination. The rule does not apply to classes of problems.

Faculty: GENETIC ENGINEERING