- Define the concept of clonal disease and chronic Myeloproliferative syndrome
- Classify the Myeloproliferative syndromes
- Define chronic myeloid leukemia
- Expose the pathogenic significance of Philadelphia chromosome
- Concept of molecular alteration bcr/abl and its involvement in the LMC
- List the clinical manifestations and laboratory data
- Explain the diagnosis and differential diagnosis
- Describe some disease forecasting criteria
- Explain the natural history of disease
- Define what a phase of acceleration and a blast crisis are
- Explain the treatment of disease
- Briefly explain other next to typical CML processes.